Genetic susceptibility to age related macular degeneration
نویسندگان
چکیده
منابع مشابه
Genetic susceptibility to age related macular degeneration.
Age related macular degeneration (AMD) is the leading cause of visual impairment in the elderly and a major cause of blindness in the developed world. The disease can take two forms, geographic atrophy and choroidal neovascularisation. The pathogenesis of AMD is poorly understood. There are undoubtedly environmental and other risk factors involved and the adverse effect of smoking is well estab...
متن کاملAssociation of Apolipoprotein E Alleles with Susceptibility to Age-Related Macular Degeneration in Iranian Patients
Background: We aimed here to investigate the association between alleles and genotypes of APOE and Age-related macular degeneration (AMD) development. Materials and Methods: After ophthalmological examination, 120 patients with confirmed AMD and 120 healthy controls were enrolled in the study. The polymorphic segment of APOE gene was PCR-amplified and sequenced to determine the frequency distr...
متن کامل[Genetic studies of age related macular degeneration].
While during the 1980s epidemiological studies searched for possible associations of environmental factors, factors of lifestyle, and cardiovascular diseases with age-related macular degeneration (ARMD), this is now perceived as a multifactorial disorder with predisposing genetic constellations and with environmental factors contributing to disease progression. The evidence which supports a gen...
متن کاملGenetic testing for age-related macular degeneration.
As the medical community has accepted that age-related macular degeneration (AMD) is a disease influenced by genetics, so too has it uncovered patterns in patients’ genetic profiles that suggest some individuals are at increased risk for initiation or progression of the disease. However, genetics is not everything, and retina specialists need to remember that AMD is a complex disorder that is a...
متن کاملTranspupilary thermotherapy of occult subfoveal choroidal neovascularization secondary to age related macular degeneration
Abstract Background: Transpupillary thermotherapy is a new treatment for subfoveal choroidal neovascularization which needs further evaluation. This study was aimed to evaluate the efficacy of transpupillary thermotherapy on regression of occult subfoveal choroidal neovascularization with or without pigment epithelial detachment in patients with age-related macular degeneration. Methods: In a ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 2000
ISSN: 1468-6244
DOI: 10.1136/jmg.37.2.83